Pre-Conference Workshop Day

Tuesday, September 26, 2023

7:00 am Registration & Morning Coffee

8:00 am Workshop A: Innovations & Technologies from Past Modality Experience to Accelerate mRNA Manufacturing & Ensure Future Success

  • John Li Director - Drug Substance, Capstan Therapeutics
  • Rajesh Beri Principal Consultant, Vial 2 Vial Bio Solutions


Innovation and technology are trailblazing the mRNA space, from batch production to automatic and digital design. However, a major challenge in mRNA manufacture is the need to modify existing procedures to effectively scale up the production process to meed global demand, while still complying with regulatory requirements.Join this workshop to discuss the future developments in the mRNA manufacturing industry and uncover the considerations required for scalability:

  • Leveraging four decades of innovation from antibody development to ensure future success of mRNA manufacturing
  • Overcoming major bottlenecks in continuous manufacturing platform development to boost productivity for mRNA therapeutics and vaccines
  • Increasing manufacturing process efficiency through smart and innovative data-driven bioprocessing

10:00 am Morning Break & Networking

11:00 am Workshop B: Leveraging Opportunities & Overcoming Challenges for the Design & Development of Multivalent mRNA Products

  • Derek O’hagan Senior Advisor - Vaccines Research & Development, GlaxoSmithKlineline
  • Gautam Sanyal Principal Consultant, Vaccine Analytics LLC.
  • Stephen Kaba Director - mRNA-Based Antigen Design, GreenLight BioSciences


Multivalent and universal mRNA-based vaccines have entered clinical development, offering a one-stop solution to a long-standing issue. However, at present, there is uncertainty surrounding how current solutions to bring these vaccines and therapeutics from bench to bedside can be integrated into the manufacturing processes, to ensure regulatory compliance without compromising process efficiency. This workshop will facilitate discussions to better understand this challenge and visualize the future of these medicines that are fully integrated into the manufacturing process

  • How to maximize process efficiency for each application, every drug modality and every therapeutic indication
  • How to design multiple antigen sequence and transcripts, and implications for large scale production
  • How to overcome bottlenecks for formulation changes and release testing, and formulation change for multivalent flu vaccine cocktails

1:00 pm Lunch Break & Networking

2:00 pm Workshop C: Accelerating Manufacturing Facility Design of the Future to Advance Modular & Large-Scale Manufacturing Development

  • Harris Makatsoris Professor - Sustainable Manufacturing Systems, King's College London


With the boom of the mRNA manufacturing industry and development of large-scale facilities to support the scale-up of mRNA-based COVID-19 vaccines, the industry has seen a surge of investment and opportunity to equitize these processes and miniaturize them into modular units, to advance the future of scale-upcapacity at reduced cost. Join this deep-dive workshop to find out how to leverage modular designs, internal architecture and resources to establish a regional solution to a global problem:

  • Advancing next generation processing for single use, closed, continuous and modular design facilities
  • Use of sigma modelling to reduce process time, facility design and internal bottlenecks
  • Revolutionizing cost-effective facility builds with modular, small print manufacturing facilities to reduce development times
  • Developing compartment-sized infrastructure, equipment and processes at GMP level for pandemic readiness

4:00 pm End of Pre-Conference Workshop Day